The Pharmacological Effects of PGF2? to Prevention and Treatment of Placenta retention and the Increase of Fertility in Postpartum Dairy Cows

• Author: Fejzo Selami - Josiana Selami
• Position: Agricultural University of Tirana, Albania - Medicine University of Tirana, Albania
• Pages: 186-190

Vol. 3 No. 3

November 2017

Academic Journal of Business, Administration, Law and Social Sciences

IIPCCL Publishing, Graz-Austria

ISSN 2410-3918

Acces online at www.iipccl.org

186

The Pharmacological E ects of PGF2 to Prevention and Treatment of Pla-

centa retention and the Increase of Fertility in Postpartum Dairy Cows

Fejzo Selami

Agricultural University of Tirana, Albania

Josiana Selami

Medicine University of Tirana, Albania

Abstract

This preliminary study was conducted to obtain a fi rst view of the role of PGF2 on placenta

expulsion, prevention of postpartum uterine infections, and fertility in dairy cows. The

objective of this study was to estimate the role of PGF2 during the excretion of placenta, for

the prevention of postpartum pathologies and fertility in dairy cows. The role of PGF2 is

well known for its stimulating abilities of the smooth musculatures and local immunity. For

the experiment we chose two groups of animals of the Holstein breed each of them containing

ten head. The cows were 3-6 years old and had normally calved. The experimental group has

been treated as follows: PGF2 (Estrumate®), 2 ml via intramuscular 2 hours a er parturition.

The treatment was repeated 8 hours a er the fi rst one. The control group was not treated and

was kept under survey so as to be compared with the indices of the experimental group. Three

results of this study were: Firstly, about the index of the placenta excretion the cows of the

experimental group have appeared it on average 13±2.4 hours a er parturition, versus 19±4.1

hours a er parturition to those of the control group. In the control group two cows have been

considered with placenta retention. Secondly, in the experimental group only one cow has

displayed signs of endometritis, whereas in the control group three. Thirdly, for the indices of

fertility there were di erences between the groups concerning both main parameters of the

Period Serve and Index of Inseminimi too. Thus the cows of the experimental group had their

average period serve 92±12.4 days versus 128±9.6 days. For the fertilizing Inseminimi in the

experimental group 1.2 doses of sperm were used up versus 1.6 doses in the control group.

We concluded that the use of PGF2 a er parturition a ects positively in the prevention of

placenta retention, in the reveal of postpartum infections and in the improvement of fertility

in cows.

Keywords: drug, PGF2, endometritis, metritis, fertility.

Introduction

The main objective of this study was the defi nition of the most appropriate therapeutic

schemes for prevention and treatment of retention of placenta and uterine infections

in dairy cows.

Uterine infections are among the most frequent disorders to a ect dairy cows during

the postpartum period (Sheldon, I. M., G. S. 2006). Some of the most frequent disorders

are placenta retention and uterine infections (endometritis and metritis). There are

many economic damages caused by these pathologies, such as: it decreases production

reduction, permanent or temporary loss of the reproductive ability, increase of the