Lifting restrictions: the role of therapeutics, testing and contact-tracing apps

• Author: Dumbrava, Costica
• Pages: 27-27

Lifting coronavirus restrictions

27

7.Lifting restrictions: The role of therapeutics, testing and

contact-tracing apps

7.1.The role of therapeutics

As stated by the WHO in its Covid-19 strategy update, it is 'ultimately the development and delivery

of a safe andeffective vaccine or vaccines and therapeutics that may enablea transition away from

some of the measures necessaryto maintain this state of low-level or no transmission'. Similarly, the

joint European roadmapto lifting coronavirus containment measures maintained that 'the

development of a safe and effective vaccine is crucial to help put an end to the Covid-19 pandemic'

and that 'societies will have to live with the virus untila vaccine or treatment is found'.

Given the great level of scientific activism and resource mobilisation, there is cautious optimism145

that there maybea Covid-19 vaccine sometime soon. The EMA estimates, however,that it could

take at least a yearbefore a vaccine against Covid-19 is ready for approval and then available in

sufficient quantities to enable widespread use.

The challenge relates not only to developingand testing a vaccine but also tomanufacturing and

distributingitto potentially billions of people who need it. According to Soumya Swaminathan, the

WHO chief scientist, in an optimistic scenario146theremay beenough doses of a vaccine next year

to immunise healthcare, followed by larger scale immunisation in 2022, though it might take four

to five years to inoculate the world. The concern with projecting unrealistically rosy timelinesfor

vaccines147is that this may soon provide ammunition to a growing number of vaccine-sceptics148

and may generally diminish publictrustand support for long-term containment measures.

Despite the great number of clinical trials, it is not clear when a Covid-19 treatment willbe available.

First of all, given the complexity of the virus, it is unlikely that a catch-all drugwill be able to tackle

all the effects of the disease. It is encouraging that there are so many candidates for Covid-19

treatments, although this variety may also be a sign of fragmentation, effort duplicationand,

generally, lack of coordination.149

7.2.The role of testing

The existence of appropriate monitoring capacity, which includes large-scale testing, is one of the

three criteria identified inthe joint European roadmapforlifting coronavirus containment measures.

The roadmap considers measures to expand testing capacity as aprecondition for lifting social

distancing measures. This includes rolling out serological testingto assess the acquired immunity

of the population and rolling out self-testing kits, 'once properlyvalidated and their reliability

ensured'. In its communicationon a phased and coordinated approach for restoring freedom of

movement and lifting internal border controls, issued on 13 May, the Commission stated that

restrictions on travel should first be lifted in areas with a comparable epidemiological situation,and

'where sufficient capabilities are in place in terms of hospitals, testing, surveillance and contact

tracing capacities'.

145C. Zimmer, K. Sheikh and N. Weiland, 'A New Entry in the Race for a Coronavirus Vaccine: Hope',

New York Times

,

20 May 2020.

146C. Hodgson, 'WHO's chief scientist offers bleak assessment of challenges ahead',

Financial Times

, 13 May 2020.

147H. Branswell, Mounting promises on Covid-19 vaccines are fueling false expectations, experts say, STAT, 6 May 2020.

148S. Zhang, 'We Don’t Even Have a COVID-19 Vaccine, and Yet the Conspiracies Are Here',

The Atlantic

, 24 May 2020.

149A. Mullard, 'Flooded by the torrent: the COVID-19 drug pipeline',

Lancet

, Vol. 395, 18 April 2020.